I played a ton of Descent 3 back in the day. One of my favorite game modes, was one where you picked up a virus from your side of the map and had to plant it on the opponents side of the map.
There was particular rooms on the opponents side of the map, that you had to deliver the virus to. After fighting your way to the room, while holding the virus, you had to come to a full stop and remain completely still for around 5 seconds to upload the virus.
There was a capture-the-flag type strategy involved to this game mode which made also really awesome.Sorry I can't remember the name of the game mode, and also I can't remember the exact details of the gamplay rules, but it was an absolutely frantic mode to play and constantly kept you moving and working together.